Re: grapefruit juice-drug interaction » bassman

Posted by Larry Hoover on May 9, 2006, at 15:00:57

In reply to grapefruit juice-drug interaction, posted by bassman on May 9, 2006, at 12:26:02

> In today's news, we have:
> http://news.yahoo.com/s/nm/20060509/hl_nm/grapefruit_dc
>
> the new discovery that furanocoumaridins (sp?) are the guys in grapefruit juice that interfere with the metabolism of some drugs.
Not to be too anal, I hope, but there are inhibitory flavonoids (naringin, naringenin) in grapefruit, as well.
As always, the dose makes the poison.
I wonder how it would change if one was to concurrently consume a 3A4 inducer, like St. John's wort, with an inhibitor. Which would win?
Lar

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grapefruit juice-drug interaction bassman 5/9/06
Re: grapefruit juice-drug interaction » bassman Larry Hoover 5/9/06
Re: grapefruit juice-drug interaction » Larry Hoover blueberry 5/9/06
Re: grapefruit juice-drug interaction Bonnie_CA 5/11/06
Re: grapefruit juice-drug interaction bassman 5/11/06
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Re: grapefruit juice-drug interaction » Bonnie_CA Larry Hoover 5/11/06
Re: grapefruit juice-drug interaction Bonnie_CA 5/13/06

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