Posted by munificentexegete on February 11, 2007, at 15:24:42
In reply to Re: low dose risperdal -- Dinah, posted by linkadge on February 11, 2007, at 11:42:57
>>which imbalance do they fix?
> Like I said, antipschotic treatment can oftentimes be associated with a normalization of the HPA axis. Some researchers think that psychosis in some people is fundimentally caused by HPA axis abnormalities, hence the strong antipsychotic actions of antiglutacortacoid drugs like RU-486.
many people have many hypotheses about many things, some people think including myself that time travel is possible, although there is no reproducable evidence supporting the cause of psychosis meaning it is merely an unsupported hypothesis at best, not scientific fact.
> A single case of something does not proove anything. The woman was taking lithium too, which has occasionally been asociated with TD. It is impossable to say that everybody treated with atypical antipsychotics is going to develop TD, even if there have been some cases of it.
do you really think there is only one case of TD with risperdal. EPS, NMS, TD, dystonias, akathisia, parkinsonism its all there in risperidone and any side effect profile worth its salt points it out. I just pointed out that court cases have been won meaning it is also legal fact too.
> There are going to be risks involved in treatment of any disease. The decision to take a medication or not is based on the personal cost/benifit ratio.
what disease?
>> once TD is proved, it is simply as bad as a typical AP
> Its not a matter of being proven or not. You have proved that TD *can* occur. That does not proove that TD will occur in any given patient.most of the studies assume EPS including TD occurs and try to point out that it produces relatively less incidence of EPS/TD. They change the doses to make it seem this way.
> Just as any given side effect for any drug will not occur in all patients.
i think it is fairly well established that risperdal causes EPS including TD. So the next issue it what is the max single dose that can induce serious eps, i think it is about aorund 5 to 6 mg depending on size weight and sex of the patient. Then what is the risk of tardive dyskinesias from long term treatment, it may be a 2% chance with 300mg, 20% chance @ 600mg and a 50% chance at 900 mg (there hasn't been enough long term studies to confirm these numbers yet). then doctors and patients could make informed choices at least regarding the potential for serious permanent brain disease from antipsychotic medication. is psychosis even a medical issue?
poster:munificentexegete
thread:730044
URL: http://www.dr-bob.org/babble/20070207/msgs/731852.html