Posted by anonymoose on November 20, 2007, at 22:51:04
In reply to Dopaminergics; how long they take to work?, posted by Mishal on November 13, 2007, at 1:02:30
Here's one poster's experience with Mirapex. He said he started feeling something after 4 days, albeit he ramped up the dosage very quickly:
http://www.dr-bob.org/babble/20030530/msgs/230157.html
I just started Mirapex yesterday too, for severe dysthymia/anhedonia/apathy/anergia (plus movement disorder symptoms: restless legs, bruxism).
I, too, was wondering why it often takes up to a few weeks for a DA agonist's effects to be felt. Shouldn't the DA receptor stimulation be felt relatively quickly? Unless the therapeutic effects have more to do with receptor up/downregulation than with the direct binding/stimulation... I dunno.
I also just started taking Selegiline too. Crossing my fingers hoping one or both will finally do the trick for me.
> I am on Trivastal(piribedil) which is a pure dopaminergic made by French pharmaceutical giant SERVIER. It is not available in U.S at the moment.
>
> My question is: How long do these dopaminergics take to provoke their real therapeutic effects? Like being on traditional antidepressants, is there a waiting period that lasts for weeks to pull off the maximum benefits?
>
> This is my first week on it. Though some obvious effects on some mental faculties are there, the real therapeutic effect is yet to be attained. I still have tremors, restless legs..
>
> Can anyone help? How long should one have to wait to get fired up on dopaminergics? Leave the issue of the drug (Trivastal) I mentioned. Just answer if you know about any of dopaminergics. Please...
poster:anonymoose
thread:794750
URL: http://www.dr-bob.org/babble/20071115/msgs/796256.html