Posted by drugdoc on March 10, 2008, at 9:15:06
In reply to Re: Mazindol (Mazinor), Tenuate, Ionomin, Mirapex, posted by Brandon on March 20, 2000, at 13:33:45
The info posted about Mirapex is ALL wrong. It is a dopamine agonist that is selective for D2/D3 dopamine receptors, not an uptake inhibitor. It is NOT an antiobesity drug (used in Parkinson's disease and RLS). DA agonists have been suggested to have some antidepressant properties, but probably work less well than even currently approved drugs.
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> > I was reading somewhere that two people taking Mirapex, another antiobesity drug, experienced relief from their depression after many failures of other meds. They weren't taking Mirapex for depression, but it was a happy side effect. Mirapex is a serotonin and norepinephrine reuptake inhibitor, probably similar to Effexor except with more anorexic effect.
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> Mirapex (pramipexole) is a selective D2/D3 reuptake inhibitor used for the treatment of movement disorders in parkinson's. It's very selective and I dont believe it acts on either serotonin or norepenephrine.
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> Brandon
poster:drugdoc
thread:27486
URL: http://www.dr-bob.org/babble/20080303/msgs/817055.html