Posted by 4WD on May 9, 2008, at 16:01:42
In reply to Wonder Why Wellbutrin was So Bad, posted by bleauberry on May 8, 2008, at 20:27:20
Hi,
Wellbutrin had a similar effect on me though not as bad and it took longer to happen. It also caused severe insomnia. I felt like I couldn't stand myself or the way I was feeling. It was horrible. And it made me smoke more, too instead of less, which is why I was taking it. It was in general a horrible experience.
Norepinephrine drugs are not good for me. I had a similar anxious reaction to nortriptyline. It's funny though, SNRI's don't do it. They actually help a little with anxiety.
Go figure,
Marsha
> Wellbutrin in 4 days took me from medium depression to suicidal ideation and almost total incapacitation. Barely able to get through work. Thought I was hiding it pretty well, but at least 5 people commented stuff like, "Smile, it aint that bad", "Don't be so depressed it's a sunny day, "You don't seem like yourself", "Are you ok?" People noticed for sure despite my years of training at hiding it.
>
> Anyway, first two days were the usual wellbutrin stuff...nervousness, heart palpitations, lousy sleep, sweating. I got through that ok. Then third day was total mind numbing calm and deep dark clouds without even a hint of any of the earlier stimulation. Weird also is that sex drive went from normal to absolute zero.
>
> If I ever wanted to feel as bad as anyone could possibly feel, all I need do is take wellbutrin. I've had periods of really really deep bad depression in my life, but it's hard to recall any as bad as what wellbutrin did.
>
> I wonder what mechanism did that?
>
> Doses were only 75mg per day. Scary to think any more might have had me driving my car into a tree to end it all.
>
> It's 24 hours since the final dose so I have hope to return to my baseline within the next day, two or three. Baseline is lousy, but a whole lot better than wellbutrin. I just wonder what mechanism it was that did that. Hard to explain, but it didn't feel like a dopamine thing or a norepinephrine thing. Maybe it was, dunno.
poster:4WD
thread:828024
URL: http://www.dr-bob.org/babble/20080430/msgs/828210.html