Posted by Phillipa on May 9, 2008, at 20:38:38
In reply to Re: SAMe Combined with Antidepressants., posted by bulldog2 on May 9, 2008, at 19:45:53
Hey guys got an official brochure at my pdocs yesterday finally its out. I could copy the many pages and post it as it explains Deplin clearer in the brochure.It does say 67% of people are partial responders or no response.Here is part of a particular paragraph " Research indicates that depressed patients with low L-methylfolate levels in the brain who have not reponded to antidepressants (ie SSRI, SNRI) may need extra L-methyfolate to boost the production of serotonin, norepinephrine, and dopamine. Why an inaddequate response to ad? Several reasons that the brain is not developing enough neurotransmitters due to in sufficient folate in the brain. This means some people might not produce enough neurotransmitts for an antidepressant to work fully.In 7 out of l0 individuals with depression they may have a specific genetic factor that limits their ability to convert folic acid to folate from the diet to L-methylfolate. This is important becuae L-methylfolate is the only form of folated used by the brain to correct a neurtransmitter imbalance linked to depression.Side effect? it is well tolerated in both short-term and long-term trials. Side effects did not differ from a sugar pill(placebo) Deplin is not associated with weight gain, sexual dysfunction. You will begin to notice a difference after taking Deplin for l-2 weeks, but the full effect may take 4-6 weeks. You may feel improvement in one or more of the following: motivation, initiative, alertness, concentration, mood, sociability. Many more pages and info. But the gist is there. Phillipa
poster:Phillipa
thread:827188
URL: http://www.dr-bob.org/babble/20080430/msgs/828270.html