Posted by undopaminergic on May 15, 2008, at 20:18:50
In reply to Re: undopaminergic:amisulpride or sulpride, posted by x-tof on May 12, 2008, at 13:58:08
> I've been looking in to both products you suggested and they seem indeed something worth to try.
> I have a slight favor for amisulpride because:
> In one study, anxiety measured by HAM-A total mean score decreased significantly more with amisulpride 50 mg/day (63%) than with fluoxetine 20 mg/day (54%)
> and I haven't found anything similar about sulpride.
> Or would a combination have more effect?Since sulpiride and amisulpride are very similar drugs, combining them is not likely to be useful.
> At what doses?
Sulpiride: 50-200 mg, two to three times daily.
Amisulpride: same dose, once or twice daily.Lower doses are more stimulating, but higher doses are possibly more useful for anxiety. The maximum recommended doses are above 1000 mg (up to about 3 grams for sulpiride), but such amounts are generally only relevant to the treatment of active schizophrenic psychosis and similar situations. Also, at high doses QT-prolongation may become a concern, especially in patients with preexisting cardiac abnormalities.
poster:undopaminergic
thread:828418
URL: http://www.dr-bob.org/babble/20080510/msgs/829319.html