Posted by undopaminergic on May 15, 2008, at 22:13:19
In reply to Re: EMSAM works 4 those w/ amphetamine mood elevation?, posted by BrightEyed+Blueberry on May 12, 2008, at 23:40:42
>
> The studies are from the 1990s , not sure if they've been 'disproven' or why it doesn't seem Much is written/said about it in the recent-post 2000 literature ? Is. There stigma regarding PEA?
>Possibly a little, due to its similarity to amphetamine. One major reason why PEA hasn't received much attention is that it isn't commercially interesting - not patentable, etc.
> Just thoughts. Any of this relate to new meds on horizon for united states approval / or what meds used succesfully in TX of depression in other countries but not here cuz of dopamine stigma?
>Methylphenidate and amphetamines are relatively frequently used as adjuncts to other antidepressants in the treatment of refractory depression. Some doctors are more fond of such treatment than others - some of whom may be almost phobic about stimulants (although the dopamine stigma isn't as strong as the opioid stigma). It's also true that some cultures are more relaxed about potentially addictive drugs than Americans and North Europeans. For example, amineptine (a dopamine reuptake inhibitor antidepressant) was never available in the US, and remained available in Brazil for some time after it was discontinued in its country of origin, France.
> If it works, under doctors careful monitoring , don't we deserve to try every option?
>PEA is readily available over the Internet as a dietary supplement, etc. but I recommend trying phenylalanine (D,L-phenylalanine - DLPA - is probably better than L-phenylalanine) before PEA. If you do try PEA while on selegiline, you should be very careful, as it elevates blood pressure.
poster:undopaminergic
thread:827789
URL: http://www.dr-bob.org/babble/20080510/msgs/829342.html