Posted by Marty on December 21, 2008, at 17:10:44
In reply to Re: Agomelatin: could 5HT(2c) action be bad for sl » Marty, posted by psychobot5000 on December 21, 2008, at 16:08:20
> The 2c receptors seem to have some paradoxical
> effects (don't they?), and I was hoping to hear
> a bit from people about them.2c is especially complex I've read. An example is that 5-HT2c antagonism seems to be favorable sexually, but 5-HT2c agonism is necessary to achieve erection. Another proof is there's some 5-HT2c AGONIST in the pipeline/clinical trials for depression/anxiety (Wyeth's Vabicaserin phase 2 or 3).. and even some prospect for psychosis if I remember well..
Later,
/\/\arty
poster:Marty
thread:869924
URL: http://www.dr-bob.org/babble/20081214/msgs/870134.html