Posted by iforgotmypassword on January 18, 2009, at 13:13:22
In reply to Re: any sign of it being released in canada, posted by SLS on January 18, 2009, at 3:49:20
it's depressing gepirone never came out. we could have got some hard in vivo human dopamine receptor occupancy data. maybe even some alpha-2 focused comparison with other drugs.
money, the alpha-2 blocking metaboite, and especially the D2 issue of buspirone were why i did not go higher with the dose, despite that theoretically it may have been able to help me.
maybe i will go back to it. i still think about it sometimes, but i really don't like messing with hard dopamine antagonists.
i am hoping that nefazodone helps mitigate excessive serotonergic input somewhere it needs to be addressed, or what i am truly hoping that it addresses it entirely, but it seems less likely to do anything at all about excess serotonergic input in the VTA, and may even likely increase serotonin there.
i feel strongly that my cluster of extrapyramidal symptoms is likely to be caused by harmful antidopaminergic effects of excess serotonergic input. but some days i really worry that it is a slowly progressing permanent neurodegenerative disease like parkinson's.
poster:iforgotmypassword
thread:874627
URL: http://www.dr-bob.org/babble/20090104/msgs/874752.html