Posted by linkadge on January 26, 2009, at 19:35:28
In reply to Re: Blood BDNF reflects brain: Potential Treatment » linkadge, posted by SLS on January 26, 2009, at 19:26:41
It doesn't say that these patients were unmedicated. As the link I posted mentioned, lithium decreased BDNF levels in bipolar patients *and* healthy controlls. Perhaps the significant decrease in BDNF levels in the study you posted was due to pharmachological intervention.
http://www.accessmylibrary.com/coms2/summary_0286-35145560_ITM"Lithium significantly decreased BDNF levels in patients with BD and healthy control participants, although BDNF levels remained lower (33%) in the BD group posttreatment. Conclusion: Decreased BDNF may constitute part of the pathophysiologic process of BD in a lithium-responsive subgroup of individuals with this disease."
poster:linkadge
thread:876377
URL: http://www.dr-bob.org/babble/20090104/msgs/876421.html