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Wellbutrin similar in effects to tricyclics?

Posted by sowhysosad on April 2, 2009, at 17:23:56

In reply to Re: Fluoxetine/sertraline and dopamine, posted by desolationrower on April 2, 2009, at 12:05:25

> i think most of bupropion's effects of through immune modulation, as its effect on reuptake is quite weak. i don't know if there is a similarity in how tca responders find buprpion.
>
> -d/r

Still no chance whatsoever that a British pdoc will prescribe bupropion for depression, but the geek in me is interested to find out.

Does anyone have experience of taking (separately) Wellbutrin and a tricyclic like imipramine or cloripramine? Are the feelings of stimulation/agitation/edginess similar at all?

I'm down to 2/3 of my previous imipramine dose and already I'm feeling better as my norepinephrine levels drop (although I'm feeling the negative effects of the drop in serotonin too!). I guess noradrenergic meds just aren't for me.


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