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Bupropion - norepinephrine uptake

Posted by sowhysosad on April 2, 2009, at 17:42:48

In reply to Re: Fluoxetine/sertraline and dopamine » sowhysosad, posted by raisinb on April 2, 2009, at 13:21:12

> That's interesting--are you sure about the source? I was on bupropion for awhile and it was definitely a dopamine drug for me. The experts on babble should be able to weigh in here.

I may have read it on Dr Ken Gillman's psychotropical site, but upon searching all I can find is this:

http://www.psychotropical.com/Antidepressants_Bupropion_Zyban.shtml

He doesn't mention the active metabolite's affinity for the norepinephrine transporter in that article, but he does say it's only a weak DRI but probably has some other unknown dopamine-enhancing effect.

I've read elsewhere that bupropion is also a weaker DRI than sertraline, interestingly.


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