Posted by linkadge on May 12, 2009, at 21:58:25
In reply to Re: Little more » linkadge, posted by SLS on May 12, 2009, at 20:43:25
>I am uncertain as to what are the effects on >serotoninergic neurotransmission after chronic >exposure. It is quite possible that >serotoninergic activity is enhanced rather than >suppressed.
I suppose thats possible, although I havn't seen studies either way. I just personally don't think that enhancement of serotonin neurotransmission has a whole lot to do with antidepressant action. Take the most effective antidepressant (ECT), some of the most recent and comprehensive studies that ECT has not appreciable or measurable effect on serotonergic neurotransmission. I guess I am just arguing with the logic: "if it doesn't increase serotonin, it can't be an antidepressant".
Linkadge
poster:linkadge
thread:895287
URL: http://www.dr-bob.org/babble/20090505/msgs/895447.html