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Re: This study makes no sence » linkadge

Posted by SLS on May 20, 2009, at 10:44:34

In reply to Re: This study makes no sence, posted by linkadge on May 20, 2009, at 8:09:56

> 1) Nowhere was the term overcrowding used in the CN mice

But, isn't the CN environment defacto overcrowding? Besides, there is probably little, if any, bonding between mother and pup. More stress. Too much competition for teats.


It really does make sense.


> 1. they used the term social enrichment

Ask the rats if they are enriched.

Enrichment is not necessarily used as a positive attribute to CN. It just means more stimulation. I have already addressed this issue with the concept of a lack of neuronal pruning, ESPECIALLY in the context of increased BDNF. Too much BDNF is not necessarily a good thing. Here, it prevents the pruning necessary for a healthy brain. Depression can come from hyperactivity in certain areas of the brain, including Brodman's area 25 (subgenual cortex). Too much BDNF at critical periods of development? Too much neurogenesis at a time where pruning should be occurring?

Your study SO makes sense.


- Scott

 

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