Posted by yxibow on May 21, 2009, at 16:44:08
In reply to Re: Avoid serotonergics after bad SRI reaction? » yxibow, posted by sowhysosad on May 21, 2009, at 5:20:19
> > But for me I think that was the first sign that I was developing a non-tardive orobuccal/orofacial tic, mostly because of Seroquel.
>
> Aha! I've only ever taken one med at a time so I can't blame it on an AP.Well.... I won't go down that road... its neither here nor there
> What's your understanding of the term "tardive"? I take it to mean "developing after some time on a med due to adaptive receptor changes".Yes, Tardive Dyskinesia and Tardive Dystonia have a /potential/ to occur after long term use of APs (there are other substances that can cause it as well but they're not nearly as relevant).
With new atypicals the general thought is 5% per year (aggregate, all of them) for an unknown period of time, while typicals are about 25% for again, an unknown but long period of time (many years to much more than a decade).
> However, my neuro insists on referring to my movement disorder as "tardive" even though it started practically the day I started Lex - implying no time for receptors to adapt. He seems to think "tardive" means "lasting a long time".
I'm not quite sure how to respond to your neurologist's description.Tardive dyskinesia will basically fully recover in at least 30% if not more of the cases, remain the same in the next 30% and possibly become worse in the remaining.
I defer to someone who is a specialist in movement disorders but without knowing the length of time you've been on Lexapro (and Zoloft ?) or any length of time on any APs you might have taken I can't get a good picture.
Certainly for Lexapro and Zoloft, actual TD is rare.
As for atypicals I can't say either... its a tossup and everyone is different but its definitely an extended period of years+ usually
But normally TD is a phenomenon not known to the patient initially -- its something that is almost always not felt with pain, and requires someone else to point it out to you.
It also doesn't just occur at one time of the day, it occurs randomly but consistently throughout the day and usually stops during sleep.
So really the only practical ways to know if there is any 'lasting' phenomenon would be to be off all medications for a while but that isn't practical I would think for your health.
A challenge to TD would be to see if this "movement" can be changed by a rx of Artane or Cogentin, or OTC Benadryl (would not suggest driving on it).
If the movement doesn't significantly get worse or in fact might even be improved, its likely not to be TD.
That doesn't mean it isn't a form of EPS if it slows down. But that's quite different.
It just doesn't seem like TD to me but you would have to go over again all of this I suspect with your neurologist or give a bit of background on what he had mentioned perhaps, if you are open to that.Its your personal medical history so I'm not asking you to post it here if you're uncomfortable.
-- best wishes-- Jay
poster:yxibow
thread:896671
URL: http://www.dr-bob.org/babble/20090515/msgs/897014.html