Posted by bleauberry on December 30, 2009, at 16:52:04
In reply to Resilience, posted by uncouth on December 29, 2009, at 21:02:54
Well, no way to know for sure obviously, but I feel you hit it right on target when your gut instincts told you serotonin is the missing link.
Julia Ross describes symptom clusters that are associated with certain neurochemical deficiencies. Obviously there is no proof of anything in psychiatry, but what she says makes a lot of sense, and she has a good deal of success in her practice.
Your symptoms fall into the category of serotonin deficiency, with a possibility of a secondary deficiency being endorphins. It appears to be exaggerated norepinephrine and dopamine, perhaps not that they are actually exaggerated, but rather they don't have enough counterbalance...serotonin, endorphins, gaba.
I have experienced the same kind of emotional sensitivity you describe. Cymbalta did not help it and made it a little worse...I think the last thing I needed was any more NE, even though Cymbalta's NE isn't much. But within several days of switching straight to Zoloft, wham, that emotional sensitivity stuff was completely gone.
poster:bleauberry
thread:931503
URL: http://www.dr-bob.org/babble/20091227/msgs/931632.html