Posted by ed_uk2010 on May 17, 2010, at 15:24:20
In reply to Re: Anyone using or experience with Desipramine?, posted by bearfan on May 17, 2010, at 15:20:10
> Any differences in efficacy with Desipramine? Is it essential the same as Tofranil with slighly less antichlorigenic side effects?
Desipramine is relatively selective as an NE reuptake inhibitor. Imipramine isn't selective at all, it hits loads of receptors.
In the treatment of severe depression, both drugs can be effective. I imagine that imipramine might be marginally more effective but often less tolerable. Only imipramine has been shown to be effective for anxiety/panic, desipramine hasn't received much study in this area.
poster:ed_uk2010
thread:947609
URL: http://www.dr-bob.org/babble/20100514/msgs/947698.html