Posted by softheprairie on May 18, 2010, at 1:28:42
In reply to Anyone using or experience with Desipramine?, posted by bearfan on May 16, 2010, at 14:36:15
Oh, oh, *raises hand* my subject that so few people IRL have in common with me -- desipramine. Yes, I am on it and love it -- you can look up my previous posts about it in the archives here; I kinda feel like I am repeating my same info whenever I venture back to this board. Well, I guess I can say again. It has been great for my depression when a bunch of other AD trials haven't. I am on 300 mg a day of it. However, to be fair, I guess I may be kinda unusual. And, even though I love it, it does still have bad side effects and risks. I think it may even be worse than imipramine in the urinary and prostate problems (I am female/don't have those probs). Also, I think it may even worsen anxiety, at least for me. I do take other things with it, and two of those help the anxiety, perphenazine (old-timey antipsychotic) and Bystolic/nebivolol (beta blocker). The beta blocker was added by my family doctor specifically to deal with the fast heartbeat the desipramine causes me, and as a bonus helps the heart palpitations, & anxiety that the desipramine brings me. The other part of my cocktail is Cytomel. I am so glad for my desipramine.
> I'm currently taking Tofranil PM (Imipramine), and its really bothering my bladder and prostate and I may discontinue soon. Is Desipramine (the metabolite of Imipramine) really worth trying and have less side effects? From what I know, it has slightly less side effects, but some say not as effective as its parent drug.
poster:softheprairie
thread:947609
URL: http://www.dr-bob.org/babble/20100514/msgs/947771.html