Posted by bulldog2 on May 21, 2010, at 16:55:16
In reply to Re: Immipramine Causes Natural Endorphins to Drop » bulldog2, posted by SLS on May 21, 2010, at 16:23:04
> > > Bulldog,
> > >
> > > How are you doing on the clomiprimine? How long have you been on it?
> > >
> > > Thanks!
> > >
> > > Laney
> >
> > Hi
> >
> > I've been on clomipramine 50 mg a couple of months. I have to admidt that I feel good for such a low dose. I feel normal and I have used neurontin high dose or lyrica high dose for purpose of feeling sociable and relaxed. They also add to the ad response. It doesn't seem like any ad addresses sociability issues. I have generally gone to neurontin for that.Perhaps nardil would work better as an ad with pro social features.
> > The only down side is my prolactin has gone over the high range and my testosterone has gone to low normal. This is probably from the clomipramine and possibly the neurontin or lyrica. So I either have to dump the clomipramine or try a dopamine agonist such as miraprex or requip.It would be interesting to see if they work.
>
> Why would you want to discontinue a drug that is working or introduce others unnecessarily? How do you know that you won't feel more social if you raise the dosage of clomipramine or give it more time to work? Is there any chance that the remaining social discomfort is psychological in origin?
>
> What was your prolactin level when tested?
>
>
> - ScottInteresting point about giving the clomipramine more time to work or raising the dose. Never having been on an AD more than a couple months I guess I'm not familiar with the evolution of a complete remission. I know from using neurontin in the past about it's pro social attributes. So I threw it into the mix.
Is it a mistake to conclude after a couple of months that this is as good as it gets(drug wise? If you knew a drug was pro social are you saying you would not introduce it at this point with the clomipramine? Actually you do make a point about my being reclusive might have psychological origins. However after being this way for over 60 years I conclude I am pretty hard wired and not likely to change at this point. So I feel that I need a gaba drug in addition to any primary AD.
As for actually stopping clomipramine it is because of my high prolactin and clomipramine has a tendecy to raise it. High prolactin will kill libido. After starting the drug my libido dropped suddenly and that led me to test my prolactin.
prolactin range 2 to 18 and mine was 21. I would like to see it in the bottom half of the range. High prolactin lowers dopamine, testosterone and hgh.
So I have a choice as to dropping the drug or introducing a prolactin suppressing med which would be in the class of dopamine agonists.
poster:bulldog2
thread:948058
URL: http://www.dr-bob.org/babble/20100514/msgs/948208.html