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Re: Anyone on Lithium and Nardil??Phillipa, others » stargazer2

Posted by SLS on June 11, 2010, at 7:43:41

In reply to Re: Anyone on Lithium and Nardil??Phillipa, others, posted by stargazer2 on June 10, 2010, at 22:12:43

> 45 mg Nardil...

I would say that the therapeutic range for severe depression is 60-90mg.

There is a formula that is sometimes used to establish a target dose:

1 mg per kg of body weight

"DOSAGE AND ADMINISTRATION
Initial dose: The usual starting dose of NARDIL is one tablet (15 mg) three times a day.
Early phase treatment: Dosage should be increased to at least 60 mg per day at a fairly
rapid pace consistent with patient tolerance. It may be necessary to increase dosage up to
90 mg per day to obtain sufficient MAO inhibition. Many patients do not show a clinical
response until treatment at 60 mg has been continued for at least 4 weeks."

http://www.pfizer.com/files/products/uspi_nardil.pdf


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