Posted by Brainbeard on January 12, 2011, at 14:42:41
In reply to Re: Advice please re. clomipramine/anafranil, posted by Gab2010 on January 11, 2011, at 14:25:07
Hi.
Clomipramine can exacerbate anxiety and inner turmoil at first. The Prozac lingering on in your blood will inhibit the breakdown of clomipramine's noradrenergic metabolite, which can result in too much stimulation.
You could get stable somewhere around the third or fourth week. For panic, only a little clomipramine can be enough. For everything else, you'll probably need more than 12(.5?) milligrams. The extra anxiety can reappear with every raise in dose. Dosage changes included, it took me at least two months to become stable on clomipramine. I have been as stupid as lowering the dose recently, only to have my OCD come back with a vengeance. I'm raising the dose again, but am still unstable.
My main side-effects are dry mouth, orthostatic hypotension = getting very dizzy when moving from a sitting/lying to a standing position and trouble getting an orgasm. Oh yeah, and brain fog. Sometimes I wonder if it's the clomipramine or I'm really that dumb.
Clomipramine is old-school, unmarketed, superior. Hope it can help you.
Current meds: clomipramine 225mg, fluvoxamine (Luvox) 50mg, dexamphetamine 5-10mg, bethanechol 20-60mg. As needed/wanted: oxazepam 5-20mg.
poster:Brainbeard
thread:949082
URL: http://www.dr-bob.org/babble/20101231/msgs/976619.html