Posted by brynb on August 3, 2012, at 7:18:01
In reply to Re: NMDA Antagonists + Synthetic Opioids » brynb, posted by phidippus on August 2, 2012, at 21:15:51
Hi Eric-
Thank you so much! Interesting about Subutex. It's been good for me in the past (though, like you said, not like Tramadol). I like the idea of using it as a prn (to cut the risk of dependence) if need be.
We'll see how I do off Tramadol. Hopefully I'll be ok w/ my combo of Lithium and Lexapro, but I need to be realistic and have a back-up plan. Oddly, I generally can't tolerate SNI's--I can't take Effexor or Cymbalta, and I can't tolerate many of the TCA's. I think it's the norepinephrine...maybe I do well with Tramadol as it's weak on norepinephrine? I took 100 mg of Tramadol when I was coming out of my last episode, but once stable with the Lithium, I did great on just 50mg of Tramadol. Is it possible that Tramadol (and Subutex, for that matter) work well because of their action on the mu and kappa receptors?
That's good to know about Memantine; I never tried it, but it sounds like it could be an option.
Thanks, Eric.
poster:brynb
thread:1022575
URL: http://www.dr-bob.org/babble/20120803/msgs/1022660.html