Posted by SLS on August 7, 2012, at 7:36:36
In reply to requip with zyprexa, posted by idelle on August 6, 2012, at 23:08:02
> What is the rationale for taking requip together with zyprexa?
I didn't know there was one.
Interesting.
The combination might help to balance dopamine activity rather than push it too far in one direction or the other. Generally speaking, Requip and Zyprexa have opposite effects at the dopamine synapse. The Zyprexa might buffer the agonist activity of Requip to produce an effect similar to Abilify. Also, Zyprexa provides serotonin 5-HT2a antagonism, which might produce antidepressant effects downstream in the PFC. Requip does not do this. I never tried this combination.
Good luck.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1022822
URL: http://www.dr-bob.org/babble/20120803/msgs/1022826.html