Posted by Novelagent on August 12, 2012, at 11:03:55
In reply to Re: requip with zyprexa » Novelagent, posted by Phillipa on August 11, 2012, at 20:11:43
> I don't get it as if it blocks serotonin what does this mean less of course but if depressed don't you need it? Serotonin that is? Phillipa
>
> http://www.drugs.com/zofran.htmlIt blocks 5-2HTA receptors, which are a type of serotonin receptors; SSRIs generally hit more than just 5-2HTA.
Also, it only modulates it somewhat-- I wouldn't say it "blocks serotonin" as in it depletes it or anything. Zofran is not associated with depression, and the idea of having too little serotonin being the cause of depression (imbalance hypothesis) has been disproven-- it turns out, people with plenty of serotonin get depressed all the time.
poster:Novelagent
thread:1022822
URL: http://www.dr-bob.org/babble/20120803/msgs/1023117.html