Posted by SLS on January 31, 2013, at 16:43:54
In reply to Prazosin - SLS need advice and info *please*!!!, posted by ChicagoKat on January 31, 2013, at 10:17:09
> I am back on IR Ritalin, and as usual, when I take a dose I get 2hrs of feeling actually human, followed by about 3hrs of anxiety. In the past, it has always been worth it to have those 2hrs, and I also used to have meds that would help with the anxiety, but they no longer work for me.
Propranolol might be worth a try.
> And the anxiety is hitting much harder than it used to; it's pretty much unbearable.
Seroquel? Remeron? Doxepin?
> I am interested in Prazosin, any advice would be appreciated, but I really hope to hear what Scott has to say.
I can't say that prazosin is acting as an anxiolytic for me, as anxiety has not been a part of my condition for quite a few years. However, it is working as an antidepressant. It also makes my sleep less choppy.
> Scott has suggested I ask my pdoc about Prazosin, and I always forget (blame it on the ect lol) because I do suffer from PTSD as well as depression and anxiety.
> So I was thinking, maybe Ritalin + Prazosin might be a good combo to fight my depression, my anxiety, my PTSD, and even my hypertension all in one!
I would definitely consider it. The only downside is a possible decrease in sex-drive.
> My only concern is that my understanding has always been that alpha blockers could potentially worsen depression...is this true?I have never heard this.
TCAs are NE alpha-1 blockers.
NE alpha-2 agonists like clonidine can be depressogenic.
If you decide to go with prazosin, it is very important to start at 1 mg given at bedtime. It can cause a great deal of dizziness at first. I recommend staying at 3 mg/day (1 mg t.i.d.) for a week before increasing the dosage. For PTSD, dosages of 6 - 12 mg/day are effective. I do well at 15 mg/day. I experience no dizziness.
Whether you try propranolol or prazosin, you can always discontinue them if they make things worse.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1036953
URL: http://www.dr-bob.org/babble/20130124/msgs/1036992.html