Posted by ChicagoKat on February 1, 2013, at 14:17:37
In reply to Re: Prazosin - SLS need advice and info *please*!!! » ChicagoKat, posted by SLS on February 1, 2013, at 12:21:16
> > Thanks for all the info Scott. I did find a couple mentions of prazosin beng used for anxiety, one in the wiki article.
> >
> > But one more question for you, if you have a moment....do you know the rationale for using prazosin for depression? Since it acts by blocking Norepi, I would think the opposite would be the result. But there is no doubt you are the expert, and I'd be very interested to hear what you have to say. Thanks so much.
> > Kat
>
> Don't think so much! It makes my brain hurt!
>
> I am no expert.
>
> Regarding prazosin, I would think that things are not so simple. I have a few ideas, though. It might be that a reduction of NE activity in the amygdala reduces anxiety and PTSD while a reduction of NE activity in the subgenual anterior cingulate cortex might be responsible for its antidepressant effect.
>
>
> - ScottSorry for making your brain hurt!!!! But see, you are so very smart, you had an answer for me, one that I don't fully understand, but that you, Mr Smarty Pants, do. Maybe an extra Prazosin will help your brain from hurting ;)
Thanks so much!
Kat
p.s. Just fyi, the reason I am asking so many questions is I want to present the idea of trying Prazosin at my next pdoc appt. So, don't get hypervigilant or anything ;), but there may be more questions coming in the next week or two, in addition to humble requests for citations to jourrnal articles, if you have any. Thanks again EXPERT.
On a steady diet of soda pop and Ritalin
-Green Day
poster:ChicagoKat
thread:1036953
URL: http://www.dr-bob.org/babble/20130124/msgs/1037065.html