Posted by Lamdage22 on August 19, 2014, at 11:00:11
In reply to Re: Sertraline immediately eliminated suicide thoughts » Lamdage22, posted by SLS on August 19, 2014, at 7:48:11
> > I don't think i abandoned sertraline prematurely. And i wonder what other effects of Sertraline may have caused me to feel better. Sigma 1 or BDNF?
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> I've read that the probability of someone responding to antidepressants is linked to the pretreatment blood level of BDNF. Higher BDNF levels indicate better response to SSRIs, even though they are not necessarily linked to initial severity of depression. I don't know if sertraline has a direct affect on BDNF production.
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> Have you tried fluvoxamine? It is the most potent of the SSRIs with respect to activity at the sigma-1 receptor. Fluvoxamine, but not sertraline, potentiated nerve-growth factor (NGF)-induced neurite outgrowth in PC12 cells.
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> - ScottNo i haven't. Sertraline is a sigma 1 antagonist though and Fluvoxamine an agonist.
I was doing better.. but im in trouble with my mother. She is seeking esoteric help, i am seeking chemical help.
Schizophrenia or Schizo-affective
Seroquel 700mg
Zyprexa 10mg
Lithium Carbonate 100mg
Metformin 1500mg
Effexor 37.5 mg
poster:Lamdage22
thread:1069951
URL: http://www.dr-bob.org/babble/20140815/msgs/1070005.html