Posted by Lamdage22 on August 19, 2014, at 13:51:51
In reply to Re: Sertraline immediately eliminated suicide thoughts » Lamdage22, posted by ed_uk2010 on August 19, 2014, at 13:41:11
Thanks, guys.
> >I don't think i abandoned sertraline prematurely.
>
> Did the restlessness happen even at low dose eg. 25mg or did you not try?I think we even tried 12.5 because we wanted to preserve this effect. I can't say im suicidal right now. But still, in a way, Sertraline helped.
>
> >Sertraline is a sigma 1 antagonist though and Fluvoxamine an agonist.
>
> Both drugs are ligands at sigma-1 receptors, but as far as I know, the definition of what constitutes an antagonist vs an agonist at this class of receptors is very poorly understood as present. It may be that fluvoxamine is worth a try but you'd need to check for drug interactions with your other medication. What are you currently taking?Seorquel 800
Zyprexa 7.5
Metformin 1500
Venlafaxine 37.5Venlafaxine could be abandoned of course.
Schizophrenia or Schizo-affective
Seroquel 700mg
Zyprexa 10mg
Lithium Carbonate 100mg
Metformin 1500mg
Effexor 37.5 mg
poster:Lamdage22
thread:1069951
URL: http://www.dr-bob.org/babble/20140815/msgs/1070017.html