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Re: SSRI's not good for older people over 50 + TCI + M » Phillipa

Posted by SLS on October 18, 2016, at 7:06:01

In reply to Re: SSRI's not good for older people over 50 + TCI + M, posted by Phillipa on October 17, 2016, at 18:36:41

> Tricyclics are definitely out as well as MAOI's. So what now. Oh also benzos included

Did you see the following passage when you read the article?

"As for the possible association between SSRI use and neurodegenerative disease, Dr Yellowlees also noted that SSRIs are not necessarily causative. "Rather, it may simply be that in the early stages of these diseases, depression and agitation are more common, and hence antidepressants are more commonly prescribed,""

I would agree that this is a possibility.

There is something known as "pseudodementia". Pseudo- obviously means "false". Pseudodementia resembles age-related dementia, but is actually the way Major Depressive Disorder presents in older people.

Bupropion (Wellbutrin) and trimipramine (Surmontil) actually enhance sleep quality. Both of these drugs should be studied for use in pseudodementia. I don't think they have been. I would look at trimipramine in particular, as it may not produce agitation the way Wellbutrin sometime does in younger people.

Phillipa, I think you might remain ill indefinitely - only because of your reluctance to explore treatments that you have not yet tried. Do you agree? That you feel much better when you are riding your bike is a clue as to how to treat your anxiety/depression. Do things improve when you are treated using psyschotherapy? It is almost as if you have been entrained to feel bad at home. Perhaps classical conditioning were operating. If it isn't a matter of problematic psychology that plagues you, perhaps you can try one of the newer antidepressants, or even an antipsychotic with antidepressant and anxiolytic properties. You don't have to be psychotic to profit from using an antipsychotic.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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