Posted by SLS on October 18, 2016, at 23:30:29
In reply to Re: SSRI's not good for older people over 50 + TCI + M » Phillipa, posted by SLS on October 18, 2016, at 7:06:01
> > Tricyclics are definitely out as well as MAOI's. So what now. Oh also benzos included
> Did you see the following passage when you read the article?
>
> "As for the possible association between SSRI use and neurodegenerative disease, Dr Yellowlees also noted that SSRIs are not necessarily causative. "Rather, it may simply be that in the early stages of these diseases, depression and agitation are more common, and hence antidepressants are more commonly prescribed,""
>
> I would agree that this is a possibility.
>
> There is something known as "pseudodementia". Pseudo- obviously means "false". Pseudodementia resembles age-related dementia, but is actually the way Major Depressive Disorder presents in older people.
>
> Bupropion (Wellbutrin) and trimipramine (Surmontil) actually enhance sleep quality. Both of these drugs should be studied for use in pseudodementia. I don't think they have been. I would look at trimipramine in particular, as it may not produce agitation the way Wellbutrin sometime does in younger people.I forgot about Trintellix (vortioxetine). It is a serotonin reuptake inhititor / receptor ligand that improves cognition as a property that is in addition to, but not dependent on, its antidepressant properties.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1092645
URL: http://www.dr-bob.org/babble/20160928/msgs/1092685.html