Posted by ed_uk2010 on March 17, 2018, at 12:15:47
In reply to How can I block Cortisol?, posted by farshad on March 16, 2018, at 7:42:29
>I wanna decrease CRF1 activity.
About your question. The drugs you listed aren't CRF-1 antagonists, if that helps. Blocking cortisol receptors or inhibiting its synthesis would not have the same effect as a CRF-1 antagonist. That is important.
Taking a CRF-1 antagonist for depression/anxiety might be possible as part of a clinical trial. But they aren't otherwise available.
I'm really not sure what you're trying to treat, to be honest. Could you give more details about your history and symptoms? I think people could offer much better advice if they knew more about you. Even leading neuroscientists only have a limited knowledge of how neurotransmitters work, so it's not possible to accurately predict medication response on this basis. Only to a vague extent.
In general, psychiatry isn't particularly scientific. Not enough is understood. Medication is generally tried based on symptom clusters and likely response because there is usually no alternative method.
So, what meds are you taking right now and how are you doing?
poster:ed_uk2010
thread:1097352
URL: http://www.dr-bob.org/babble/20180212/msgs/1097396.html