Posted by ed_uk2010 on March 17, 2018, at 14:11:31
In reply to Re: How can I block Cortisol?, posted by farshad on March 17, 2018, at 12:39:49
Hi,
So, you've had some genetic tests, maybe something online? Who did the tests?
>But these cortisol blockers I listed why wouldnt they help for an Overactive CRF1? Since they decrease cortisol which would lead to less cortisol circulating around and that would lead to CRF1 downregulation?
If you took a drug which decreased cortisol, your cortisol levels would most likely drop below normal levels. Your body would then try to overcome this in order to bring cortisol levels back to normal. CRF may be upregulated to try and do this. Your body would not downregulate CRF in response to low cortisol, because that would cause your cortisol to become even lower. The body always tries to achieve hormonal balance (homeostasis).>I think I just have some mutations in my CRF1 making it overactive, here are some weird SNPs I got that I cant find any info about on the internet.
If you're concerned about this, you could be tested for high cortisol. I mentioned the tests in my previous post. Doctors usually test for high cortisol if a patient has signs that it is high, for example:
Loss of fat in the arms and legs, plus an increase in fat at the back of the neck, chest, and abdomen.
A round puffy face, usually reddish.
Development of large purple stretch marks on the body.
Skin has started to bruise easily.
>There is a drug called....I get where you're coming from, but you are getting way ahead of yourself :) If you think you might have high cortisol due to the tests you've had so far, you would need to be tested properly for high cortisol before taking any drugs. Otherwise, it would not be safe. Look at the symptoms above and if you have them, a doctor may do a test for high cortisol.
Now IF your cortisol levels were proven to be elevated, and the elevation was sustained and pronounced, a doctor might prescribe something for this after further investigation.
poster:ed_uk2010
thread:1097352
URL: http://www.dr-bob.org/babble/20180212/msgs/1097399.html