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Re: Selegiline Phenylalanine nemesis

Posted by sfy on September 14, 2004, at 22:04:17 [reposted on September 15, 2004, at 18:33:45 | original URL]

In reply to Re: Selegiline Phenylalanine nemesis, posted by nemesis on September 14, 2004, at 21:40:10

> After over 12 years of constant depression in various forms, that never responded very well to anything, this has turned out to be the holy grail for me. My psychiatrist saw me within two weeks of my starting on it and he said I looked the best he has ever seen me. I have a full range of emotions on this combo (that's a good thing), and on most days I feel better than I can ever remember previously in my life.
>
> I have stabilized at:
> 1. 500 mg/day DLPA upon awaking, 30 mins. before food, taken along with 50 mg P-5-P (active form of Vitamin B-6, which helps amino acid absorption).
> 2. 10 mg/day selegiline hydrochloride right after breakfast.
>
> I had increased anxiety and insomnia the first week, but that's gone now and there's really no other side effect. It's clean, and it works fast and well.
>
> D-phenylalanine converts to PEA, while L-phenylalanine converts to PEA and tyrosine, which in turn converts to noradrenaline and dopamine. PEA is an endogenous amphetamine-like compound found in lower levels in many depressed people and higher levels in people who are in love. It boosts mood quickly like amphetamine, but without tolerance. The problem is its amazingly short half life (less than half a minute) - but the selegiline solves that by blocking PEA degradation.
>
> Let me know if you have any questions. I have researched this a lot - and it's really working for me.


Thanks - I'm starting on 5 mg. Selegiline plus DLPA next week (I've got to wait for mirtazapine to wash out). I'm hoping it will help my dysthymia/anhedonia/lack of motivation. I figured I'd give it a shot before having to deal with Parnate.

How important is it to have the P-5-P instead of just the usual B6?


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