Posted by karaS on September 14, 2004, at 23:33:32 [reposted on September 15, 2004, at 18:33:47 | original URL]
In reply to Re: Selegiline Phenylalanine nemesis, posted by nemesis on September 14, 2004, at 21:40:10
> After over 12 years of constant depression in various forms, that never responded very well to anything, this has turned out to be the holy grail for me. My psychiatrist saw me within two weeks of my starting on it and he said I looked the best he has ever seen me. I have a full range of emotions on this combo (that's a good thing), and on most days I feel better than I can ever remember previously in my life.
>
> I have stabilized at:
> 1. 500 mg/day DLPA upon awaking, 30 mins. before food, taken along with 50 mg P-5-P (active form of Vitamin B-6, which helps amino acid absorption).
> 2. 10 mg/day selegiline hydrochloride right after breakfast.
>
> I had increased anxiety and insomnia the first week, but that's gone now and there's really no other side effect. It's clean, and it works fast and well.
>
> D-phenylalanine converts to PEA, while L-phenylalanine converts to PEA and tyrosine, which in turn converts to noradrenaline and dopamine. PEA is an endogenous amphetamine-like compound found in lower levels in many depressed people and higher levels in people who are in love. It boosts mood quickly like amphetamine, but without tolerance. The problem is its amazingly short half life (less than half a minute) - but the selegiline solves that by blocking PEA degradation.
>
> Let me know if you have any questions. I have researched this a lot - and it's really working for me.
>
>
> > Just wondering how the selegiline and DLPA combo is working for you? (or anyone else who might be taking it, Kara?)
> >
>
>
I am not taking this now. I tried taking just selegiline 5 mg. for a couple of days. (I was going to add DLPA in the following days and possibly up the dosage of the selegiline to 10 mg. as the experiment progressed.) I had a somewhat paradoxical reaction to it though. I took it at around noon time and felt tired for most of the afternoon (had to drink a full cup of coffee which I don't usually do in the afternoon). Then around 9:00-10:00 that evening I started feeling the stimulation from it and couldn't sleep. So I decided that this might not be the best thing for me to try right now. I haven't given up on it entirely though (I just think that there may be some other health-related reasons that are standing in the way of this working well for me now) and I'm still holding out hope for the patch.Nemesis, if you have any insight into why I might have reacted like I did to the selegiline, I'd love to hear it. It would be easier to understand if I just had the initial paradoxical reaction. I don't suppose you reacted like that to it at first, did you?
I would love for this combination to work for me. It sounds so ideal - easy, inexpensive, clean and yet brain healthy (or so they claim).
Also, do you take anything for sleep with this regimen? It doesn't sound like it but I just wanted to be sure.
sfy,
If you do decide to try this, please post your results. I'd be very interested in seeing how your fared on it.
Kara
poster:karaS
thread:377600
URL: http://www.dr-bob.org/babble/alter/20040901/msgs/391204.html