Posted by jujube on December 21, 2004, at 16:50:34
In reply to Re: speculations on acetylcholine and NE » jujube, posted by zeugma on December 20, 2004, at 18:18:32
Posting inquiries on various drugs and supps here, where some real experts can be found (not myself of course- I never took a high school chem class and would have failed it if I had, but of course I failed everything in those days...) is not a gullible thing, but a rational thing to do. There are trustworthy people here!
-- I agree that there are trustworthy people here, and I have come to rely upon and trust the advice and information I have gleaned from this site. It's the often conflicting and at times biased information that one finds on some websites that lead me to seek out more information or some sort of confirmation as to the veracity of the information. I guess I am becoming less naive and learning to recognize the "spin" that is sometimes used to perhaps enhance a products credibility.
> Yes, I checked it out, and it is interesting. It seems that the authors believe that cholinomimetic drugs would be especially good for inattentive ADD. This definitely catches my attention (pardon my strange sense of humor). It seems to me, intuitively, that inattentive ADD'ers are the 'daydreaming' type, and that this propensity to daydream would be a mark of cholinergic overactivity, not underactivity. In fact, I believe that inattentive ADD is more likely to result in depression than the hyperactive kind (although this may be utterly wrong- I need to research this, it should be easy enough to pull up an abstract or two from pub Med, but I am lazy- this is an important topic and I should look into it tonight). I would have thought the daydreaming would profit from specific REM suppression, which selective NE reuptake inhibitors perform (for the link, check out this study on the differential effects of stimulants and NE reuptake inhibitors: http://www.sro.org/pdf/863.pdf
-- The study was interesting. I read it quickly, and will re-read it so that the facts really sink in. No to be morbid (and completely off topic), but what happens to the dogs when the experiments/study are over? I hope they don't have to be put down. For some reason, I can handle the thought of tests being done on rats, but I hate the thought of those poor dogs being subjected to such a thing. I love animals, and am a bleeding heart to boot.
And although PsychoBabbleLand is full of horror stories about this med, including my own, if you go to http://crazymeds.org/, you will find atomoxetine (Strattera) in heavy rotation as an ADHD med. (You'll also find them, or at least Jerod, site owner, bashing TCA's. It's good to get a spectrum of opinions.)-- At this point, the only stimulant-like med I will be willing to try is Provigil. With respect to Crazymeds, I have visited that site a number of times. It's interesting. Question. When Jerod talks about "Mouse's" experience, is he talking about a real mouse that he gives meds too? Or is it a joke and he's talking about his computer mouse? Just something I had wondered.
> I don't know what to conclude from all this. but if DMAE is working for you, that is fantastic!-- The combination of DMAE, NADH and Vitex seems to be doing something. I am starting to feel like my old self again. Still hyper and easily distratcted, but, heh, that is really my old self so I can't complain. I hope the combo continues to work because it is such a nice feeling (it's kind of freaking me out - in a good way!).
Anyways, take good care of yourself. Until next time.Tamara
poster:jujube
thread:430543
URL: http://www.dr-bob.org/babble/alter/20041212/msgs/432544.html