Posted by linkadge on August 14, 2005, at 5:03:47
In reply to Re: The link for DMT cures depression » linkadge, posted by barbaracat on August 13, 2005, at 21:57:14
Its funny because the way that SSRi's increase serotonin is different from how lithium increases serotonin.
Lithium actually has a strong serotogenic effect, but it interacts with a few serotonin receptors ie 5-ht2a/c so that PKC is not activated.
Serotonin is calming at certain receptors, and upping and other receptors. So to say that a bipolar doesn't need serotonin may or may not be true.
Lithium interacts with the 5-ht1b receptor which affects GSK-3b signaling. GSK-3b seems to have a strong effect in regulating the circadian rhythm. A link below.
http://www.news-medical.net/?id=11642
Actually some people treat their mood disorders solely thought manipulation of sleep. Proponents say its effective and has less burdonsome side effects than conventional treatments.
Linkadge
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