Posted by JLx on September 22, 2005, at 19:42:50
In reply to First Day Magnesium Glycinate and More Questions, posted by blueberry on September 22, 2005, at 18:19:35
> I'm wondering, how important is the glycine component of Mg glycinate. I mean, does the glycine make more gaba or something like that? Is the amount of glycine even significant enough to make any difference, or is it just a bioavailability thing? I'm worried that if it does convert to gaba, that over a few months of use it could cause tolerance. Any thoughts?
> So today I took a Solgar 400mg tab, broke in three pieces, took one with breakfast, one with lunch and one in mid afternoon. I honestly was expecting either nothing, or something bad to happen.
>
> Around noon, something strange happened. My jitteriness...inner jitters and finger jitters and knee jitters...calmed down significantly. I became overall more calm and yet energetic and motivated at the same time. Zero depression today. It really took me by surprise. I was able to get away with a little bit less xanax today. And quite honestly, if I had taken a double dose of xanax it would not have helped as much as the Mg glycinate did. I was surprised. Hope it continues. Sometimes these first day wonders end up pooping out. I am worried about tolerance.
>
> But clearly, Mg glycinate blocked something that was causing my physical jitteriness and psychological anxiety.
>
> How important is the glycine component? Is tolerance an issue to worry about?
>
> Thanks for all your help. You folks are wonderful.I don't know if tolerance is the right word.
I had a dramatic response from first taking magnesium and that level lasted about 2 months. Someone else at the time had an equally dramatic upturn and it lasted for him a shorter time. I'm not trying to be discouraging at all, just be forewarned that the MOSTness of the good feeling may fade.
But for me now, it's been 2 and a half years and I can still feel magnesium doing me a lot of good. It FOR SURE prevents suicidal ideation for me. And it helps my depression overall. It's one thing that I can always tell the difference with if I get careless and start taking less. There are real reasons that magnesium works as it does having to do with various bodily functions that require magnesium. 300+ enzymatic functions.
I'm not sure what is happening when that initial reaction starts to lessen. I think Larry H. said once that it's like whatever needs magnesium gets "topped up" after a time, and so those things are not as turned on by the magnesium. It becomes steady instead of brilliant. (Only he said it much more scientifically! ;))
I think it's a good sign that you're having a powerful initial reaction as it may mean that even if it decreases you will feel overall better consistently with long term use.
About whether glycinate is the relevant factor, I couldn't say. I take glycine itself in addition to mg glycinate at night as I find it relaxing. It doesn't seem to poop out.
400 mg is not that much. Are you a small person? Just curious.
Glad it's working for you! :)
JL
poster:JLx
thread:558254
URL: http://www.dr-bob.org/babble/alter/20050812/msgs/558268.html