Posted by linkadge on November 27, 2006, at 12:23:30
In reply to Re: Exercise benefit is Anandamide not endorphins, posted by aeon on November 26, 2006, at 20:53:30
>schizophrenics have greatly elevated anandamide >which they intially thought was implicated in >causing it, now they realise that the worse the >schizophrenia the less anandamide they have. It >is the body's ANTI- psychosis mechanism.
You're on the ball, I read that studies too. Yes, anandamide has antidopaminergic properties. It potentiates 5-ht1a receptors, and antagonizes 5-ht2a like some atypical antipsychotics, as well as inhibiting limbic dopamine release.
Thats why too much weed makes people sleepy and unmotivated.
I'd have to reread it, but it also was points to why people with schizophrenia use marajuanna, to try and perhaps counteract a sluggish endocannabanod system?Linkadge
poster:linkadge
thread:706985
URL: http://www.dr-bob.org/babble/alter/20061118/msgs/707825.html