Posted by Tomatheus on December 1, 2006, at 0:18:14
In reply to Re: Natural COMT inhibitors, posted by Meri-Tuuli on November 26, 2006, at 12:46:20
Blueberry & Meri-Tuuli,
Thank you for the information on rhodiola rosea. I was not aware of the fact that rhodiola has been shown to have COMT-inhibiting properties -- my knowledge of the herb's mechanisms is rather limited -- and it's helpful to know that it does.
A while back, I did come across a study on rhodiola that suggested that the herb has cholinergic properties, which is the main reason why I haven't tried it as of yet. Cholinergic meds and supplements that I've taken in the past seem to aggravate the melancholic/anxious aspect of my depressive disorder (which I now believe is a double depression with both melancholic and atypical components), causing me to experience feelings of akathisia. But I guess it's conceivable that rhodiola's cholinergic effects might be relatively weak and that its benefits might outweigh its drawbacks.
So, I may consider giving rhodiola a try at some point in the future, considering that it has COMT-inhibiting properties. It's still not next on my list of things to try, but I think it might be worth a try if other options fail.
Thanks again for the info.
Tomatheus
> > I saw somewhere that Rhodiola Rosea has COMT inhibition mechanisms. But it has other mechanisms too which may or may not be of interest to you.
>
> Yeah this is what I found too. They don't really know how rhodiola rosea works, they do reckon at COMT inhib. It feels rather like a stimulant through.
poster:Tomatheus
thread:707161
URL: http://www.dr-bob.org/babble/alter/20061118/msgs/709226.html