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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Ted_Brosnan on December 5, 2004, at 10:18:42
Hello,
It looks like I found a psychiatrist willing to rx a MAOI. He wants to discuss something else before that, I will meet him on tuesday.
Is it true that half of food would be prohibited? I have seen some lists and they don't look that awful...
I remember that I have asked this before, but which one you think should I try first for my Social Anxiety? Parnate or Nardil?
Is it true that Parnate is more effective?!
Thanks,
Ted.
Posted by ed_uk on December 5, 2004, at 10:51:05
In reply to Parnate, Nardil and dietary restrictions?!, posted by Ted_Brosnan on December 5, 2004, at 10:18:42
Hi Ted,
It's good to hear from you!
Parnate might be more effective for your ADD-type symptoms but probably not for your anxiety. Some people find Nardil more effective for anxiety but as always YMMV. Maybe you should try both (not at the same time!) to see which you prefer.
Regards,
Ed.
Posted by jclint on December 5, 2004, at 10:59:30
In reply to Parnate, Nardil and dietary restrictions?!, posted by Ted_Brosnan on December 5, 2004, at 10:18:42
Hi Ted, I'm in a similar position to you, I have found a pdoc willing to prescribe MAOIs and am currently washing out from effexor.
Lol, the food restrictions...
Firstly you must bear in mind that the original restrictions were significantly overstated and based on anecdotal evidence. Since 1996 there have been numerous studies that have suggested more liberal restrictions. There's plenty about that on this site, I believe Dr Bob even has a page specifically on it. Bear in mind that your doctor may not be aware of contemporary research into this issue and may need some education from yourself - there's plenty of credible clinical studies to bring along.I am treating symptoms similar to yours - I am going to start on Nardil. My reasoning for this is:
- Nardil has unique effects on GABA receptors which some researchers link with SA
- There is little clinical research into Parnate's effeciacy in SA, but quite a lot into Nardil's
- Parnate is apparently less forgiving in terms of dietary restrictions
- Parnate generally causes more insomnia than NardilParnate has the upper hand in terms of weight gain and sexual side effects, but I'm going to see how I do on Nardil before deciding they are too much. After all, there are many to whom these side effects aren't an issue / disappear after a while.
I think anxietynetwork is pretty much the only site that recommends Parnate over Nardil. They cite Parnate's stimulating effect for this. If stimulation is something you think you need, then perhaps it is preferable, but the GABA effect of Nardil gives it preference in most doctor's eyes. You might want to look at what www.socialfear.com has to say (I'm sure you've seen it before :). I have certainly seen more accounts of success with Nardil over Parnate for SA, but that's not to say there aren't some for whom Parnate is more effective.
Good luck to you, there seems to be several people on here who are looking to start MAOIs in the near future, including myself :)
J
Posted by ed_uk on December 5, 2004, at 14:59:11
In reply to Re: Parnate, Nardil and dietary restrictions?!, posted by jclint on December 5, 2004, at 10:59:30
Hi Ted and Jclint :-)
Jclint summarises the important points...
'- There is little clinical research into Parnate's effeciacy in SA, but quite a lot into Nardil's
- Parnate is apparently less forgiving in terms of dietary restrictions
- Parnate generally causes more insomnia than Nardil'......... I have often wondered how important the GABAergic effect of Nardil is in social anxiety. The GABAergic effect of Nardil is *not* the same as a benzodiazepine. Unlike Parnate, Nardil is a GABA transaminase inhibitor which means that it inhibits the breakdown of GABA. In the UK, an anticonvulsant called vigabatrin is available- it is a GABA transaminase inhibitor. Behavioural/psychiatric side effects are very common. Ahhh :-(
Some of the common side effects of vigabatrin are...
drowsiness, fatigue, dizziness, anxiety! aggression, depression and headache. Less common side effects include... psychosis, amnesia, double vision, weight gain! and agitation.
Of course, vigabatrin and Nardil are different drugs but to be honest.... I'm not sure that I want to take a GABA transaminase inhibitor.
Regards,
Ed.
Posted by Willyee on December 6, 2004, at 0:09:36
In reply to Parnate, Nardil and dietary restrictions?!, posted by Ted_Brosnan on December 5, 2004, at 10:18:42
> Hello,
>
> It looks like I found a psychiatrist willing to rx a MAOI. He wants to discuss something else before that, I will meet him on tuesday.
>
> Is it true that half of food would be prohibited? I have seen some lists and they don't look that awful...
>
> I remember that I have asked this before, but which one you think should I try first for my Social Anxiety? Parnate or Nardil?
>
> Is it true that Parnate is more effective?!
>
> Thanks,
> Ted.
I found them both to be quite different.Im not gonna recomend one over the other because obviously id be partial to the one i use,in general there are great responses found on the net to both.www.remedyfind.com has a rating of both from personal experieances might want to check them out,its a great site.
One thing i will say is,if your depression is very severe,then you might want to consider parnate iniitaly cause i believe its the fastest acting of the Maois,i know i had a totaly response from it within 48 hrs.Also although parnate is stimulating,it is most during the initial week or so,after time it tends to become a claming agent,i myself am trying to find a stimulate now to add to it.Which ever you choose welcome to the MAOI club,good luck
Posted by SLS on December 6, 2004, at 0:43:29
In reply to Re: GABA transaminase inhibition, posted by ed_uk on December 5, 2004, at 14:59:11
> Hi Ted and Jclint :-)
>
> Jclint summarises the important points...
>
> '- There is little clinical research into Parnate's effeciacy in SA, but quite a lot into Nardil's
> - Parnate is apparently less forgiving in terms of dietary restrictions
> - Parnate generally causes more insomnia than Nardil'.
>
> ........ I have often wondered how important the GABAergic effect of Nardil is in social anxiety. The GABAergic effect of Nardil is *not* the same as a benzodiazepine. Unlike Parnate, Nardil is a GABA transaminase inhibitor which means that it inhibits the breakdown of GABA. In the UK, an anticonvulsant called vigabatrin is available- it is a GABA transaminase inhibitor. Behavioural/psychiatric side effects are very common. Ahhh :-(
>
> Some of the common side effects of vigabatrin are...
>
> drowsiness, fatigue, dizziness, anxiety! aggression, depression and headache. Less common side effects include... psychosis, amnesia, double vision, weight gain! and agitation.
>
> Of course, vigabatrin and Nardil are different drugs but to be honest.... I'm not sure that I want to take a GABA transaminase inhibitor.
>
> Regards,
> Ed.
>
>Vigabatrin can also cause visual field defects that I believe are irreversible.
- Scott
This is the end of the thread.
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