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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 15 of 15. This is the beginning of the thread.
Posted by blueberry on September 22, 2005, at 18:19:35
I'm wondering, how important is the glycine component of Mg glycinate. I mean, does the glycine make more gaba or something like that? Is the amount of glycine even significant enough to make any difference, or is it just a bioavailability thing? I'm worried that if it does convert to gaba, that over a few months of use it could cause tolerance. Any thoughts?
So today I took a Solgar 400mg tab, broke in three pieces, took one with breakfast, one with lunch and one in mid afternoon. I honestly was expecting either nothing, or something bad to happen.
Around noon, something strange happened. My jitteriness...inner jitters and finger jitters and knee jitters...calmed down significantly. I became overall more calm and yet energetic and motivated at the same time. Zero depression today. It really took me by surprise. I was able to get away with a little bit less xanax today. And quite honestly, if I had taken a double dose of xanax it would not have helped as much as the Mg glycinate did. I was surprised. Hope it continues. Sometimes these first day wonders end up pooping out. I am worried about tolerance.
But clearly, Mg glycinate blocked something that was causing my physical jitteriness and psychological anxiety.
How important is the glycine component? Is tolerance an issue to worry about?
Thanks for all your help. You folks are wonderful.
Posted by JLx on September 22, 2005, at 19:42:50
In reply to First Day Magnesium Glycinate and More Questions, posted by blueberry on September 22, 2005, at 18:19:35
> I'm wondering, how important is the glycine component of Mg glycinate. I mean, does the glycine make more gaba or something like that? Is the amount of glycine even significant enough to make any difference, or is it just a bioavailability thing? I'm worried that if it does convert to gaba, that over a few months of use it could cause tolerance. Any thoughts?
> So today I took a Solgar 400mg tab, broke in three pieces, took one with breakfast, one with lunch and one in mid afternoon. I honestly was expecting either nothing, or something bad to happen.
>
> Around noon, something strange happened. My jitteriness...inner jitters and finger jitters and knee jitters...calmed down significantly. I became overall more calm and yet energetic and motivated at the same time. Zero depression today. It really took me by surprise. I was able to get away with a little bit less xanax today. And quite honestly, if I had taken a double dose of xanax it would not have helped as much as the Mg glycinate did. I was surprised. Hope it continues. Sometimes these first day wonders end up pooping out. I am worried about tolerance.
>
> But clearly, Mg glycinate blocked something that was causing my physical jitteriness and psychological anxiety.
>
> How important is the glycine component? Is tolerance an issue to worry about?
>
> Thanks for all your help. You folks are wonderful.I don't know if tolerance is the right word.
I had a dramatic response from first taking magnesium and that level lasted about 2 months. Someone else at the time had an equally dramatic upturn and it lasted for him a shorter time. I'm not trying to be discouraging at all, just be forewarned that the MOSTness of the good feeling may fade.
But for me now, it's been 2 and a half years and I can still feel magnesium doing me a lot of good. It FOR SURE prevents suicidal ideation for me. And it helps my depression overall. It's one thing that I can always tell the difference with if I get careless and start taking less. There are real reasons that magnesium works as it does having to do with various bodily functions that require magnesium. 300+ enzymatic functions.
I'm not sure what is happening when that initial reaction starts to lessen. I think Larry H. said once that it's like whatever needs magnesium gets "topped up" after a time, and so those things are not as turned on by the magnesium. It becomes steady instead of brilliant. (Only he said it much more scientifically! ;))
I think it's a good sign that you're having a powerful initial reaction as it may mean that even if it decreases you will feel overall better consistently with long term use.
About whether glycinate is the relevant factor, I couldn't say. I take glycine itself in addition to mg glycinate at night as I find it relaxing. It doesn't seem to poop out.
400 mg is not that much. Are you a small person? Just curious.
Glad it's working for you! :)
JL
Posted by nolvas on September 22, 2005, at 21:30:51
In reply to Re: First Day Magnesium Glycinate and More Questions » blueberry, posted by JLx on September 22, 2005, at 19:42:50
I also recently started taking Chelated Magnesium (Glycinate) from Solgar and yes it does definitely make me feel calmer.
The symptoms of magnesium deficiency mimic anxiety conditions exactly and also Mitral Valve Prolapse is indicated in anxious persons, which again responds to Magnesium treatment. So there are many people I believe who have an anxiety disorder and it's biological in origin. Psychologically I still feel like avoiding certain situations but the generalised anxiety is totally gone when I take Magnesium. No heart palpatations and lack of confidence from feeling ill out of the blue.
I'm hoping to find a good source of Magnesium Taurate as this is supposed to be even better than Glycinate.
Posted by JLx on September 23, 2005, at 6:56:19
In reply to Re: First Day Magnesium Glycinate and More Questio, posted by nolvas on September 22, 2005, at 21:30:51
> I'm hoping to find a good source of Magnesium Taurate as this is supposed to be even better than Glycinate.Vitamin Shoppe, Cardiovascular Research brand, has it.
It's actually cheaper ordering the same product, which also comes from VS, from Amazon as they are discounting it 20%.
JL
Posted by maddy4 on September 23, 2005, at 9:16:27
In reply to Re: Magnesium taurate » nolvas, posted by JLx on September 23, 2005, at 6:56:19
this thread is so interesting b/c i was just looking into starting to take mag. glysinate for anxiety/panic attacks but then found another message board where several people had INCREASED anxiety from it so it made me decide against - but now reading this i am confused b.c it seems to be HELPING all of you w/ anxiety! thoughts?
Posted by JLx on September 23, 2005, at 9:26:03
In reply to Re: Magnesium taurate, posted by maddy4 on September 23, 2005, at 9:16:27
> this thread is so interesting b/c i was just looking into starting to take mag. glysinate for anxiety/panic attacks but then found another message board where several people had INCREASED anxiety from it so it made me decide against - but now reading this i am confused b.c it seems to be HELPING all of you w/ anxiety! thoughts?
You won't know until you try. And if you do and it doesn't feel good, there's no harm done. A poor response should reverse itself very shortly.
I think one explanation for increased anxiety following magnesium supplementation may be because of the importance of the magnesium/calcium ratio.
If you have too much calcium and not enough magnesium you won't even get the calcium you think you are because it needs magnesium to be utilized. So sometimes I think what may happen is that the extra magnesium potentiates the calcium and it's the calcium that increases anxiety/depression.
If someone is ordinarily supplementing with calcium and/or eating a high calcium diet, I would recommend cutting out or down calcium at the same time as taking magnesium, especially if anxiety increases. Iow, it may be only a temporary thing and magnesium in the long run may alleviate anxiety.
OR people may just react differently to it. My sister finds magnesium stimulating and calcium calming. I'm just the opposite.
JL
Posted by maddy4 on September 23, 2005, at 9:59:29
In reply to Re: Magnesium taurate » maddy4, posted by JLx on September 23, 2005, at 9:26:03
now i am taking abt 2,500 of calcium a day - throughout the day - would i take the mag gly. w/ it or at sep times? TIA
Posted by Declan on September 23, 2005, at 15:07:22
In reply to First Day Magnesium Glycinate and More Questions, posted by blueberry on September 22, 2005, at 18:19:35
When I had glycine I'd have a heaped teaspoonful before bed. I need to get some more, or magnesium diglycinate and some bulk taurine. Maybe it will deepen my sleep.
Declan
Posted by JLx on September 23, 2005, at 17:23:16
In reply to Re: Magnesium taurate JLx, posted by maddy4 on September 23, 2005, at 9:59:29
> now i am taking abt 2,500 of calcium a day - throughout the day - would i take the mag gly. w/ it or at sep times? TIA
That is a lot of calcium.
Unless you know for sure from experimenting with taking/not taking it previously, I would seriously suggest not taking it at ALL when first supplementing with magnesium. For a week to a month. Whatever you're taking that much calcium for will probably not be affected in that length of time. But it MAY be definitely affecting your magnesium status in a very negative fashion.
CONSERVATIVE advice is to take calcium and magnesium in a 2:1 ratio. That would mean you would need to take 1,250 mg of magnesium now. That's pretty hard to do when you're not used to it as it can cause diarrhea unless taken in fairly small doses at a time, or something like 500-700 mg per day.
Some nutritonists recommend calcium/magnesium in a one to one ratio, which is almost impossible to achieve at your current 2500 mg calcium dose.
I don't begin to understand the chemistry in this article, but what bits I do understand sound like some possiblilities involved with depression and anxiety, such as arichidonic acid, inflammatory cytokines, nitric oxide and free radicals. And magnesium is the calcium channel blocker that can prevent that excess.
"CALCIUM, THE EXCITOTOXIC “HIT MAN”
"Normal levels of calcium inside the neuron allow normal functioning, but when excessive calcium builds up inside neurons, this activates a series of enzymes, including phopholipases, proteases, nitric oxide synthases and endonucleases.(1,3) Excessive intraneuronal calcium can also make it impossible for the neuron to return to its resting state, and instead cause the neuron to "fire" uncontrollably. (1,3) Phospholipase A2 breaks down a portion of the cell membrane and releases arachidonic acid, a fatty acid. Other enzymes then convert arachidonic acid into inflammatory prostaglandins, thromboxanes and leukotrienes, which then damage the cell. (1,3) Phospholipase A2 also promotes the generation of platelet activating factor, which also increases cell calcium influx by stimulating release of more glutamate. (3) And whenever arachidonic acid is converted to prostaglandins, thromboxanes, and leukotrienes, free radicals, including superoxide, peroxide and hydroxyl, are automatically generated as part of the reaction (1-3, 16). Excessive calcium also activates various proteases (protein-digesting enzymes) which can digest various cell proteins, including tubulin, microtubule-proteins, spectrin, and others. (1,3) calcium can also activate nuclear enzymes (endonucleases) that result in chromatin condensation, DNA fragmentation and nuclear breakdown, i.e. apoptosis, or "cell suicide". (3) Excessive calcium also activates nitric oxide synthase which produces nitric oxide. When this nitric oxide reacts with the superoxide radical produced during inflammatory prostaglandin/leukotriene formation, the supertoxic peroxynitrite radical is formed (3,17). Peroxynitrite oxidizes membrane fats, inhibits mitochondrial ATP-producing enzymes, and triggers apoptosis (17). And these are just some of the ways glutamate -NMDA stimulated intracellular calcium excess can damage or kill neurons!"
http://smart-drugs.net/ias-excitotoxins.htm
I supplemented with calcium for years until I got a calcium kidney stone. That was no fun. I felt better after that because I quit taking supplements, though I didn't know enough to attribute it to the less calcium making me less anxious and depressed.
How I felt overloaded on calcium and magnesium deficient was extremely irritable, very sensitive to noise and lights as an irritant -- not to mention people! haha. I felt like a nervous wreck when things went wrong, especially something pressing like having to be somewhere at a certain time. Sometimes I would just get so stressed I would sit and cry to reduce the tension of feeling like I was just "losing it". I was emotionally labile like that, sensitive to aggravation and rejection. Slightly paranoid. And depressed, of course.
If you feel like that, then seriously consider cutting out all that calcium and trying magnesium for even a short time. You may feel better right away as I did. MUCH better. It makes me sick that I felt SO terrible all those years, for lack of this information.
Of course, it may be different for you.
But to answer your actual question....:) I'd advise taking them at separate times. Take the magnesium on an empty stomach or with meals low in fat as fat interferes with its absorption.
JL
Posted by maddy4 on September 23, 2005, at 18:08:54
In reply to Calcium » maddy4, posted by JLx on September 23, 2005, at 17:23:16
OMG JL - what an informative post! i never even CONSIDERED that calcium could be contributing to my anxiety, irritablity and agitation (which brought me to this board!)!!!
i take 2,500 calcium for a few reasons - b/c i thought calcium was a sedative / nerve calming + b/c i am thin and osteoperosis runs in the fam and i smoke (on and off) and also , b/c clacium is supposed to help burn fat and i like being thin and strive to stay that way!!...
so - i upped my calcium years ago and at this juncture am a nervous wreck ...googling medications + considering drugs (tried lexapro for two days this week - hated it, now have a rx for WB but have made no decisions - not sure abt going the antiD route) - would rather do vitamins and a benzo as needed.
anyway - your information is huge - i ordered some Mag Glysinate online yesterday - so should be here next week. so how much calcium and how much mag gly. should i take EXACTLY and how far apart. must adnit - am scared to go cold turkey on calcium b/c of it fat burning effects!
also, i wonder what other vitamin overdoses i am taking.???? i take essentail fatty acids + evening prim + flax seed + multi B ...just added extra B1 for panic. also L Lysine (also just added) and Liquid iron (floradix) + herbs. and i just ordered liquid Kyolic w/ B1 and B2 - heard its good for anxiety (via "nutritional healing" book)
thoughts? you are so helpful - i really appreciate it! :)
Posted by blueberry on September 23, 2005, at 20:33:31
In reply to First Day Magnesium Glycinate and More Questions, posted by blueberry on September 22, 2005, at 18:19:35
Second day with Mg Glycinate just as impressive as the first. Actually, it's not the antidepressant part I'm looking for, but the anti-anxiety part. I've been taking 1.5mg xanax for a few weeks, and today didn't even feel the need for any. I took .75mg anyway just to avoid sudden withdrawals. But to be able to cut my benzo dose in half instantly is like wow. I'm still wondering though if it's the magnesium or the glycine that's causing the calming of nerves.
For anyone skeptical or scared of trying it, just buy a brand in tablet form, so you can cut it into small pieces to experiment with. I've been cutting a 400mg tab into thirds and spread them throughout the day. Actually today I got by with only about 300mg.
Hope the good antianxiety effect continues. It's nice not to have to rely on xanax as heavily as I was. Please please don't poop out on me Mg.
Posted by JLx on September 23, 2005, at 22:24:05
In reply to Re: Calcium JLx, posted by maddy4 on September 23, 2005, at 18:08:54
Hi Maddy,
>am scared to go cold turkey on calcium b/c of it fat burning effects!
I don't think you need to worry about this or about osteoporosis to the tune of 2,500 mg/day of calcium supplementation.
I looked for the evidence of calcium supplementation promoting fat burning. Most of those studies, some of which have been refuted by newer ones, emhasized that it was dairy products not just calcium itself. There may have been other factors in the dairy that promoted the weight loss, such as Vit D. And just how effective were they?
And how much of a difference might calcium/dairy supplementation make?
http://www.nutrition.org/cgi/content/full/133/1/268S
© 2003 The American Society for Nutritional Sciences J. Nutr. 133:268S-270S, January 2003
calcium intake has been variously estimated to explain from 3% to perhaps as much as 10% of the total variation in adult weight, a relatively small portion of the total variability.A good very recent summary:
Dairy Data Deliver Mixed Messages: Wading through milk's cloudy connection to weight loss http://docnews.diabetesjournals.org/cgi/content/full/2/10/8
More to consider:
http://www.jabfp.org/cgi/content/full/18/3/205
Several of the previously reviewed studies suggest that calcium from dairy products affects weight loss more than calcium derived from dietary supplements.17 Preliminary data point to some other component in dairy products, possibly whey protein, effecting the weight-loss effect of calcium.26 Whey protein provides a multitude of bioactive substances that may work synergistically with the calcium to alter lipid metabolism. ... Calcium is not a magic bullet in the battle against obesity, although it may play a small, but significant, role. The affect of dairy products or calcium is probably greatest in those people whose adipocyte status is changing, such as during weight loss, age-associated weight gain, and growth. ...
An important concept to remember is that calcium does not seem to be effective unless a calorie restriction is already in place. Replacing other sources of protein with low-fat dairy products may help augment weight loss. ...All patients should be encouraged to consume 3 to 4 servings of low-fat dairy products every day.Published online ahead of print April 12, 2005, 10.1210/jc.2004-2205
http://www.rapp.org/url/?UR2M7QHP
Design: This is a substudy of an ongoing, double-blind, randomized, controlled trial of calcium supplementation. End points were assessed at 30 months.
Conclusions: Calcium supplementation of 1 g/d does not produce biologically significant effects on body weight, and its hypotensive effect is small and transient in most women.http://www.nutrition.org/cgi/content/full/133/1/245S
2003 The American Society for Nutritional Sciences J. Nutr. 133:245S-248S, January 2003
This review of randomized trials of increased dairy product or calcium intake obtained little evidence to support the hypothesis that calcium or other components of dairy products have a measurable impact on body weight in generally healthy humans. Although seven of nine randomized studies of increased dairy product intake did not detect an increased weight gain in the dairy product group, interpretation of this finding is limited by the inability to accurately determine the extent of compensation for the energy intake from the added dairy products. Only one of 17 randomized trials of calcium supplementation found a significantly greater weight loss (or smaller weight gain) in the calcium-supplemented group, and it could be argued that this is close to what would be expected on the basis of chance alone.
http://www.obesityresearch.org/cgi/content/abstract/13/8/1344
Obesity Research 13:1344-1353 (2005)
Discussion: We found no evidence that diets higher than 800 mg of calcium in dairy products or higher in fiber and lower in glycemic index enhance weight reduction beyond what is seen with calorie restriction alone.http://ajpregu.physiology.org/cgi/content/full/286/4/R669
Our results with rodents have led us to critically evaluate the evidence that calcium reduces obesity in humans. Most of the calcium supplementation studies have been retrospective analyses, and these are subject to reporting bias. Epidemiological studies are difficult to interpret, because calcium intake covaries with the intake of several other nutrients (4, 14, 18, 25), some of which are just as likely as calcium to influence obesity. In rats, macronutrient selection is influenced by calcium status (45). It may be that humans provided with calcium alter their food selection, and this contributes to changes in body weight. In summary, we believe that the extant data do not support a simple relation between dietary calcium and obesity in rodents, and the issue remains an open question for humans.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15711601&query_hl=15
CONCLUSIONS: Increased dietary calcium/dairy foods in an energy-restricted, HP diet does not affect weight loss or body composition. Weight reduction following increased protein diets is associated with beneficial metabolic outcomes that are not affected by protein source.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15969206&query_hl=19
The scientific community is in agreement that there is a pressing need for large clinical trials to assess the effect of Ca on weight reduction and to investigate whether weight loss could be achieved easier with Ca supplements or dairy products. It has yet to be learned what amount of Ca would be optimal for those purposes and what influence, if any, an individual's current Ca intake and existing weight might play. Additionally, it is still hard to pinpoint which component(s) in dairy foods have a role in weight reduction and whether they act alone or in synergism with Ca.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15817848&query_hl=23
Am J Clin Nutr. 2005 Apr;81(4):751-6.
BACKGROUND: Previous results suggested that increased intake of dairy calcium is associated with reduced weight and fat mass.
CONCLUSION: Increased intake of dairy products does not alter body weight or fat mass in young, healthy women over 1 y.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15354150&query_hl=23
Girls on a high-calcium diet gain weight at the same rate as girls on a normal diet: a pilot study.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15113738&query_hl=23
Notably, dairy sources of calcium markedly attenuate weight and fat gain and accelerate fat loss to a greater degree than do supplemental sources of calcium. This augmented effect of dairy products relative to supplemental calcium is likely due to additional bioactive compounds, including the angiotensin-converting enzyme inhibitors and the rich concentration of branched-chain amino acids in whey, which act synergistically with calcium to attenuate adiposity. These concepts are confirmed by epidemiologic data and recent clinical trials, which indicate that diets that include > or =3 daily servings of dairy products result in significant reductions in adipose tissue mass in obese humans in the absence of caloric restriction and markedly accelerate weight and body fat loss secondary to caloric restriction compared with diets low in dairy products. These data indicate an important role for dairy products in both the prevention and treatment of obesity.http://jcem.endojournals.org/cgi/content/full/89/2/632
In summary, an antiobesity effect of calcium reported by others during weight-stable conditions led us to hypothesize that supplemental calcium during caloric restriction would enhance loss of body weight and fat. Although we did not find a statistically significant effect of supplemental calcium on fat or body weight in obese women undergoing moderate weight loss, the direction of change suggests that over a longer period of time and with a larger number of subjects a reliable effect might be observed. [This was a 25 week study]http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15761180
Data do not support recommending dairy products for weight loss.http://jcem.endojournals.org/cgi/content/full/90/7/4411
Dietary calcium, obesity and hypertension--the end of the road?http://www.obesityresearch.org/cgi/content/full/13/8/1301
The Beginning of the End for the Dietary Calcium and Obesity Hypothesis?Since you are already thin, and since the effect of calcium even IF it's as fat burning as some studies have suggested would still make only 3-10% of a difference, I don't think you have anything to worry about. ESPECIALLY for a short term trial of a month or two.
It sounds like 3-4 servings of dairly, or 900-1200 mg of calcium would suffice for any possible weight effect AND to prevent osteoporosis. Iow, NO supplementation needed.
Consider that chilled poultry. ;)
I've got some more data on osteoporosis that I'll post tomorrow.
JL
Posted by maddy4 on September 26, 2005, at 8:13:35
In reply to Re: Calcium and weight loss » maddy4, posted by JLx on September 23, 2005, at 22:24:05
thanks JL, for all of the articles! so can you tell me exactly how much calcium and how much magnesium i should be taking? the calcium supplements i take have magnesium (from mag oxide chelate) and zinc. so with those pills i *have* been taking what equals to 2,500 mg of calcium and 1,250 mg of magnesium oxide. so how should i tweak this when my mag glysinate arrives this week???
TIA! :)
Posted by JLx on September 27, 2005, at 20:53:44
In reply to Re: Calcium and weight loss JLx, posted by maddy4 on September 26, 2005, at 8:13:35
> thanks JL, for all of the articles! so can you tell me exactly how much calcium and how much magnesium i should be taking? the calcium supplements i take have magnesium (from mag oxide chelate) and zinc. so with those pills i *have* been taking what equals to 2,500 mg of calcium and 1,250 mg of magnesium oxide. so how should i tweak this when my mag glysinate arrives this week???
> TIA! :)Magnesium oxide is absorbable at about 5%, according to studies that Larry Hoover posted in previous posts. So you haven't actually been getting 1250 mg of magnesium but more like sixty something mg which is way overpowered by all that calcium.
How much total zinc are you taking in a day? Any vitamin D with that calcium?
You won't know how you react with the magnesium until you try it. In my opinion, the best trial to see if magnesium will relieve some anxiety and depression which the calcium may be making worse, is to not take ANY calcium, but just magnesium. Try it for a day. If it feels ok, then try it for a week. If it still feels ok, then try it for a month or two. Then try adding back the calcium and see if you feel more nervous and irritable. Then you know.
If you're a person weighing 100-125 lbs, 400 - 600 mg of magnesium would be good to start. If more, then figure 4.5 mg of magnesium per pound of body weight.
Take the magnesium on an empty stomach and space it out to prevent diarrhea.
I was reminded again this week, btw, of the nasty effect of calcium supplementation on me. I've been having little cramps in my feet at night, which is usually a magnesium thing, but I'm taking plenty of magnesium. So I thought I'd try calcium too. I took only about 180 mg of calcium with 600 mg of magnesium one night. I woke up a couple hours later to use the bathroom and noticed I felt remarkably cranky and irritable. I had a headache like I get when I've been grinding my teeth in my sleep. I thought, great, I'm losing my grip more than usual and was bummed out. THEN I remembered the calcium. I know not everyone shares my experience with calcium as many people find it calming, but for me it's just the opposite. I've been just shuddering to think of your 2500 mg a day! ;)
I hope the magnesium glycinate helps you.
What other supplements do you already take?
JL
Posted by maddy4 on October 1, 2005, at 19:17:31
In reply to Re: Calcium and magnesium » maddy4, posted by JLx on September 27, 2005, at 20:53:44
>
> I was reminded again this week, btw, of the nasty effect of calcium supplementation on me. I've been having little cramps in my feet at night, which is usually a magnesium thing, but I'm taking plenty of magnesium. So I thought I'd try calcium too. I took only about 180 mg of calcium with 600 mg of magnesium one night. I woke up a couple hours later to use the bathroom and noticed I felt remarkably cranky and irritable. I had a headache like I get when I've been grinding my teeth in my sleep. I thought, great, I'm losing my grip more than usual and was bummed out. THEN I remembered the calcium. I know not everyone shares my experience with calcium as many people find it calming, but for me it's just the opposite. I've been just shuddering to think of your 2500 mg a day! ;)
>
> I hope the magnesium glycinate helps you.
>
> What other supplements do you already take?
>
> JLOMG!!!!! JL! this had me LOLing! i TOTALLY have had those feet cramps - PLENTY of times!!! -they are heinous!!!!!!! no one knows what im talking abt when i've mentioned them - then i read your post and laughed! i am not insane!!!! (or maybe i am :) ) but hooray that it is from calcium and/or lack of magnesium and not some degenerative disease!!!! will fill in the rest of other ??s on other thread down below soon! you are awesome! thanks!
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