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Re: Which is worse: Zyprexa weight gain or Risperdal

Posted by SLS on February 28, 2001, at 6:48:56

In reply to Re: Which is worse: Zyprexa weight gain or Risperdal » katrina, posted by SalArmy4me on February 27, 2001, at 20:34:47

Hi SalArmy4me.

> Zyprexa has more of a chance of helping you than Risperdal

This might not be true.

> because it has been proven to have effects on serotonin

Risperdal is a more potent serotonin 5-HT2a receptor antagonist than is Zyprexa. It is this property that is being focussed upon regarding the action of these drugs.

> thus enhancing the actions of antidepressants. I'll have to get that study for you...

Please do.

It is my gut feeling that you are right, and that more people glean an antidepressant response to Zyprexa than to Risperdal, especially when combined with Prozac. However, there are more anecdotal reports of the successful use of Risperdal than Zyprexa. This may be, in part, because Risperdal has been around a few more years than Zyprexa.

Either drug is a fine selection as an adjunct in treating depression, bipolar or unipolar.


- Scott

 

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