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Re: Which is worse: Zyprexa weight gain or Risperdal » Cam W.

Posted by SLS on February 28, 2001, at 6:59:19

In reply to Re: Which is worse: Zyprexa weight gain or Risperdal » SalArmy4me, posted by Cam W. on February 27, 2001, at 21:30:00

Dear Cam,


> It is probably their mood stabilizing effects that augment antidepressant activity.

I don't buy this. I think their potential as adjuncts lie in a more direct antidepressant effect. My guess is that some ratio of 5-HT2/DA2 antagonism works to potentiate dopaminergic activity "downstream". This would account for some of the latency I have seen once an immediate improvement wanes, only to return three to four weeks later. Besides reading of others' descriptions, I have some "insiders" information.

I am not the drug guy. I am the wild guess guy.

:-)


- Scott

 

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