Posted by JohnL on July 21, 2001, at 9:31:24
In reply to Re: What do I do now? » JohnL, posted by Else on July 21, 2001, at 6:59:45
Yeah, it does have some effect on increasing serotonin activity, but in a totally different way than SSRIs. While SSRIs hold existing serotonin in place and let it build up by accumulation, Zyprexa instead stimulates the release of fresh new serotonin. I like that a lot better.
Zyprexa does have anti-histimine effects, and I too am sensitive to that. But after a week most of that subsides. And after a month it's nearly gone completely.
Stimulants I was referring to are Ritalin, Adderall, or my favorite, Adrafinil (European mailorder). Adrafinil is a kinder gentler stimulant that increases norepinephrine activity without increasing norepinephrine levels, and it also has some indirect effects on stimulating dopamine D2 receptors. Unlike the other stimulants which you can feel almost immediatley, Adrafinil takes days to weeks to come on.
> Well I don't know. It does work on serotonine does it not? I do terribly on drugs like Zoloft and Effexor, they make me shake and twich like crazy. And I'm very sensitive to the sedative effects of anti-histamines. Too sensitive. One girl here once told me Zyprexa felt like a anti-histamine and that's not encouraging. I would lean toward stimulants more than APs. Especially considering the possible weight gain on Zyprexa. I know a lot of people here swear by it but I am really put off by anti-psychotics because my brother turned into a complete weirdo on Risperdal (which he was taking for anxiety and temper tantrums). He just became Zombie-like. I don't know anyone who takes Zyprexa but I would be wary about it for that very reason.
>
> >Personally I have seen more people get well with antipsychotics and/or stimulants than antidepressants, mood stabilizers, etc.
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> Which stimulants are you reffering to?
>
>
> Thanks for the suggestions
>
> > Hi,
> > One word, Zyprexa. I have yet to see any single drug with as much promise as this one. Just because it is named as an antipsychotic, don't let that scare you. It has been shown in clinical studies to be effective for a wide . get well with antipsychotics and/or stimulants . Personally I have seen more people get well with antipsychotics and/or stimulants than antidepressants, mood stabilizers, etc.han antidepressants, mood stabilizers, etc.variety of psychiatric symptoms In my own experience, and it's just my opinion, not fact (what in psychiatry is fact anyway?) Zypexa blows the ADs in the weeds. It works on dopamine, norepinephrine, and serotonin, all three, and has an anti-anxiety component to it. Mileage of course varies, but in this hit and miss game I believe Zyprexa offers better odds for success than just about any other choice I can think of.
> >
> > Sedation is heavy at first. Don't worry, it goes away, and the good sleep might be a welcome relief anyway. Weight gain is often a problem, but can be avoided by drinking a large glass of water before meals, and by being careful with snacks. Best overall results when combined with Prozac.
> > John
poster:JohnL
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