Posted by kregpark@yahoo.com on January 19, 2002, at 14:30:32
In reply to MAOI efficacy » SLS, posted by TSA West on January 19, 2002, at 5:14:19
Hi,
I think it still holds that MAOI's are superior for aytpical depression
Nowadays polypharmacy is common so more alternatives exist.
Still, I think enhanced steady state dopamine enhancement reduces fear, passivity, pain, introversion, low energy, and anhonesia (sp? - ie; lack of pleasure).In my opinion the nice thing about MAOI's especially low dose Eldepryl is:
- Robust pro-dopamergic action
- Steady state effect
- Dopaminergic neuroprotection
- Delay Parkinson's onset (SP more likely to get Parkinson's)
- For atypicals / phobics / bipolar lows, great "base" to add to, preventing an otherwise susceptibility to sedation and sexual side effects.Hope that made a bit of sense! :)
kreg park
The 3 MAOI's Nardil, Eldepryl, Parnate, have different profiles so if Nardil is too sedating than Parnate, or high dose Elderpyl can be tried.
Most people will probably find Nardil quite activating.> I wish you well.
>
> I think you're on the right track with MAOIs in general, considering that you had a response to Nardil in the past.
>
> And further, your 'rejection-sensitivity' sounds a lot like Social Anxiety Disorder (a specific disorder ameliorated most effectively by MAOIs).
>
> Selegiline (MAOI-B) could provide you some relief from the intrinsic sedation of the Nardil (http://www.dr-bob.org/tips/split/Selegiline-for-depression.html).
>
> 60 mg of selegiline is the equivalent of 30 mg of Nardil, according to one of Dr. Bob's associates.
>
> I am glad that you have progressed in the learning of your emotions, such that you can present them to us-- and thus we can help you more thoroughly in your quest for a good medication regimen....
>
> TSA West^^^^^^^^^
poster:kregpark@yahoo.com
thread:90736
URL: http://www.dr-bob.org/babble/20020116/msgs/90776.html