Posted by djmmm on January 21, 2002, at 14:33:54
In reply to Re: MAOI efficacy » bob, posted by kregpark@yahoo.com on January 21, 2002, at 2:16:39
> Hi Bob,
>
> (Some people use SP short for Social Phobia).
> Yes, it has been well established in studies that Parkinson's patients are five times more likely to have have SP *precede* development of Parkinson's.can you post these abstracts, or a link, please...
I am aware of a D2 receptor connection (low D2 receptor binding in some people with social phobia)...PET scans of parkinsons patients show increased D2 binding (via the use of D2 agonists)...so Im a bit confused...
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1801535&dopt=Abstract
> Yes also the dopamine point you brought out. Parkinson's meds don't usually work as antidepressants.
> However MAOI's (including Elderpyl at high dose) also significantly boost serotonin and norepineprhine.
> Nardil boost serotonin more than dopamine and norepihephrine (and also GABA at higher doses).
>
> kp
>
>
> > Yet another question:
> >
> > How can an antidepressant, like the MAOIs etc. increase dopamine levels, without the risk of EPS? I thought that was exactly why APs inclined to do that.
poster:djmmm
thread:90736
URL: http://www.dr-bob.org/babble/20020116/msgs/90997.html