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Re: Klonopin + Nardil = Major Anxiety

Posted by Kneeko on September 4, 2007, at 15:54:23

In reply to Re: Klonopin + Nardil = Major Anxiety » Kneeko, posted by Jedi on September 3, 2007, at 22:39:55

> Kneeko,
> In your situation, if the depression or anxiety is not being handled completely at 75mg, I would take it up to 90mg.
>
> I have never taken Zyprexa, but I would think that unless you are bipolar or have psychotic depression, it might not be the best augmentor. I do take a small dose of quetiapine(Seroquel)-25mg to counteract the insomnia induced by Nardil. At this low dosage quetiapine has an antagonistic effect on the histamine H1 receptor, which accounts for its beneficial effect on insomnia. At higher dosages this med can affect the dopamine and serotonin receptors.
> Be Well,
> Jedi
>
>
> > A question, if you weigh 220-230 lbs(102-103kg), would a dose of 75 mgs often be insufficient? Nardil seems to be helping a little bit, but feels like something is missing, Side effects don't bother me too much.
> >
> > Also another few questions, is Zyprexa really a decent augmentation agent for Nardil? it seems like it would exacerbate depression given the fact that it blocks dopamine.
> >
> >
>
>


Thankyou, Jedi. I did have a manic episode about 18 months ago on Nardil, at which time I was placed on Zyprexa for the last 18 months, it doesn't seem to really do that much.

Was interested in what agents you think might augment Nardil? The SSRI's did nothing, and Noradrenaline and Stimulant based meds cause agitation. Currently Im trying 2.5mg Zyprexa, and 300mgs lithium for augmentation. Would Nortryptiline or Mirapex(perhaps both) be good agents to try Nardil?

Thankyou


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