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Re: Dopamine agonists...why aren't more people usi » linkadge

Posted by Brody on October 27, 2007, at 16:35:31

In reply to Re: Dopamine agonists...why aren't more people usi, posted by linkadge on October 27, 2007, at 15:48:28

Yes.... I've read that, too. I'm sorry, I thought that was covered in the link I inserted, but I guess not.

Here are two references from PubMed docs:


".........the antidepressants that bind selectively the norepinephrine transporter might produce their therapeutic effect by raising the extracellular concentration of dopamine besides that of norepinephrine......"


and,


"Selective norepinephrine reuptake inhibitors exploit the fact that dopamine transporters are absent in prefrontal cortex, so dopamine has to hitchhike a ride on the norepinephrine transporter in order to be inactivated. Thus, blocking norepinephrine transporters leads to an increase in both dopamine and norepinephrine levels in prefrontal cortex..........."

Janet


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poster:Brody thread:791344
URL: http://www.dr-bob.org/babble/20071027/msgs/791814.html