Posted by florence on December 6, 2007, at 0:58:14
In reply to Re: Here's one!, posted by B2chica on November 29, 2007, at 15:12:16
FWIW amisulpride (Solian) is used as an antipsychotic and also used for depression and dsythmia per SLS's drug sheets....
renal excretion-- 12 hr half-life...Yrs ago I took notes that said: amisulpride: D2 agonist (opposite of pramipexole (Mirapex)
It stimulates all POST synaptic DA receptors including D3- indirectly by raising DA levels--
Mirapex, however, lowers DA levels but stimulates D3 receptors directly and therefore more selectively.Don't know if this still applies....I only know I had no luck with Ser and Norep drugs so Dopamine seemed only option.....Hopes dashed when a poster told me it was not available in the USA.
I have the binding affinity comparisons for Mirapex and Requip...somewhere if anyone wants me to post them.....basically D2 and D3 differences.
florencethanks sig. i was kinda looking in the parkinson area but was wondering if there were others, i think that restirol...or what's the one for the restless leg thing, was one.
> anyway. trying to look at a case study from a different angle.
> not for me.
> thanks for the info.
poster:florence
thread:797625
URL: http://www.dr-bob.org/babble/20071204/msgs/799046.html